The Importance of Chemistry in Cancer Therapy
Chemistry plays a pivotal role in the development of novel cancer therapies, particularly in the design and optimization of targeted treatments.
MS01 showed a significant reduction in PDE5 inhibitors’ side effects, such as headache and dizziness, compared to existing treatments.
Improved bioavailability: MS01 has shown to have a higher bioavailability compared to existing PDE5 inhibitors, which means it can be more effective in treating erectile dysfunction.
Lower risk of drug interactions: MS01 has a lower risk of drug interactions compared to existing PDE5 inhibitors, which makes it a safer option for patients who take multiple medications.
Reduced side effects: MS01 has shown to have a significant reduction in side effects such as headache and dizziness compared to existing PDE5 inhibitors.
Pharmacokinetic Properties
MS01 has demonstrated favourable pharmacokinetic properties, including:
Improved bioavailability: MS01 has shown to have a higher bioavailability compared to existing PDE5 inhibitors.
Improved pharmacokinetic profile: MS01 has a more predictable and stable pharmacokinetic profile compared to existing PDE5 inhibitors.
Clinical Trials
MS01 has undergone several clinical trials to evaluate its safety and efficacy.
By combining these techniques, Bello’s team is able to design and synthesize novel compounds that can effectively target HIV proteins, such as the viral capsid protein, gp120.
Predict the binding affinity of a molecule to a specific protein
Identify potential binding sites on a protein
Simulate the effects of a molecule on a biological system
For example, researchers can use computational modelling to simulate the binding of a potential HIV treatment compound to the gp120 protein.
